DNA sensing via the cGAS/STING pathway activates the immunoproteasome and adaptive T‐cell immunity

The immunoproteasome is a specialized type of proteasome involved in MHC class I antigen presentation, antiviral adaptive immunity, autoimmunity, and is also part of a broader response to stress. Whether the immunoproteasome is regulated by DNA stress, however, is not known. We here demonstrate that...

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Detalles Bibliográficos
Autores principales: Wang, Xinyuan, Zhang, Huabin, Wang, Yuqin, Bramasole, Laylan, Guo, Kai, Mourtada, Fatima, Meul, Thomas, Hu, Qianjiang, Viteri, Valeria, Kammerl, Ilona, Konigshoff, Melanie, Lehmann, Mareike, Magg, Thomas, Hauck, Fabian, Fernandez, Isis E, Meiners, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106989/
https://www.ncbi.nlm.nih.gov/pubmed/36912165
http://dx.doi.org/10.15252/embj.2022110597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106989/
https://www.ncbi.nlm.nih.gov/pubmed/36912165
http://dx.doi.org/10.15252/embj.2022110597

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