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Synthesis and screening of cyclic diketone indanedione derivatives as future scaffolds for neutrophil elastase inhibition

Human neutrophil elastase (HNE) and proteinase 3 (Pr3) released from neutrophils at inflammatory sites are the major causes of pathogens in chronic obstructive pulmonary disease (COPD) and various lung tissue derangements, among which cystic fibrosis and blockade of airway passages are chronic. Thes...

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Detalles Bibliográficos
Autores principales:	S., Meena, S., Jubie, C., Pramila, A., Manal T. N., S., Gigi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107027/ https://www.ncbi.nlm.nih.gov/pubmed/37077993 http://dx.doi.org/10.1039/d3ra00106g

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