Cargando…

Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats

INTRODUCTION: Previous studies in Ren-2 transgenic hypertensive rats (TGR) after 5/6 renal ablation (5/6 NX) have shown that besides pharmacological blockade of the renin-angiotensin system (RAS) also increasing kidney tissue epoxyeicosatrienoic acids (EET) levels by blocking soluble epoxide hydrola...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chábová, Věra Čertíková, Kujal, Petr, Vaňourková, Zdeňka, Škaroupková, Petra, Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Tesař, Vladimír, Hammock, Bruce, Imig, John, Maxová, Hana, Červenka, Luděk, Vaněčková, Ivana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107074/ https://www.ncbi.nlm.nih.gov/pubmed/31770762 http://dx.doi.org/10.1159/000504137

Ejemplares similares

Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats
por: Kujal, Petr, et al.
Publicado: (2014)

Renoprotection Provided by Additional Diuretic Treatment in Partially Nephrectomized Ren-2 Transgenic Rats Subjected to the Combined RAS and ET(A) Blockade
por: Vaněčková, Ivana, et al.
Publicado: (2019)

Endothelin type A receptor blockade attenuates aorto-caval fistula-induced heart failure in rats with angiotensin II-dependent hypertension
por: Kala, Petr, et al.
Publicado: (2023)

Kidney Response to Chemotherapy-Induced Heart Failure: mRNA Analysis in Normotensive and Ren-2 Transgenic Hypertensive Rats
por: Jíchová, Šárka, et al.
Publicado: (2021)

20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats
por: Sedláková, Lenka, et al.
Publicado: (2018)

Deleterious Effects of Hyperactivity of the Renin-Angiotensin System and Hypertension on the Course of Chemotherapy-Induced Heart Failure after Doxorubicin Administration: A Study in Ren-2 Transgenic Rat
por: Kala, Petr, et al.
Publicado: (2020)

Impaired renal autoregulation and pressure-natriuresis: any role in the development of heart failure in normotensive and angiotensin II-dependent hypertensive rats?
por: Honetschlägerová, Zuzana, et al.
Publicado: (2023)

Effects of Epoxyeicosatrienoic Acid-Enhancing Therapy on the Course of Congestive Heart Failure in Angiotensin II-Dependent Rat Hypertension: From mRNA Analysis towards Functional In Vivo Evaluation
por: Kala, Petr, et al.
Publicado: (2021)

Pharmacological Blockade of Soluble Epoxide Hydrolase Attenuates the Progression of Congestive Heart Failure Combined With Chronic Kidney Disease: Insights From Studies With Fawn-Hooded Hypertensive Rats
por: Vacková, Šárka, et al.
Publicado: (2019)

Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats
por: Hrdlička, Jaroslav, et al.
Publicado: (2019)

Early Renal Vasodilator and Hypotensive Action of Epoxyeicosatrienoic Acid Analog (EET-A) and 20-HETE Receptor Blocker (AAA) in Spontaneously Hypertensive Rats
por: Walkowska, Agnieszka, et al.
Publicado: (2021)

Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure
por: Vacková, Šárka, et al.
Publicado: (2019)

The treatment with sGC stimulator improves survival of hypertensive rats in response to volume-overload induced by aorto-caval fistula
por: Gawrys, Olga, et al.
Publicado: (2023)

High Salt Intake Increases Blood Pressure in Normal Rats: Putative Role of 20-HETE and No Evidence on Changes in Renal Vascular Reactivity
por: Walkowska, A., et al.
Publicado: (2015)

Empagliflozin Is Not Renoprotective in Non-Diabetic Rat Models of Chronic Kidney Disease
por: Hojná, Silvie, et al.
Publicado: (2022)

Epoxyeicosatrienoic Acid Analog and 20-HETE Antagonist Combination Prevent Hypertension Development in Spontaneously Hypertensive Rats
por: Baranowska, Iwona, et al.
Publicado: (2022)

Sodium Glucose Cotransporter-2 Inhibitors: Spotlight on Favorable Effects on Clinical Outcomes beyond Diabetes
por: Čertíková Chábová, Věra, et al.
Publicado: (2022)

The treatment with trandolapril and losartan attenuates pressure and volume overload alternations of cardiac connexin-43 and extracellular matrix in Ren-2 transgenic rats
por: Sykora, Matus, et al.
Publicado: (2023)

Effects of Renal Denervation on the Enhanced Renal Vascular Responsiveness to Angiotensin II in High-Output Heart Failure: Angiotensin II Receptor Binding Assessment and Functional Studies in Ren-2 Transgenic Hypertensive Rats
por: Honetschlägerová, Zuzana, et al.
Publicado: (2021)

Effects of Trandolapril on Structural, Contractile and Electrophysiological Remodeling in Experimental Volume Overload Heart Failure
por: Jarkovská, Dagmar, et al.
Publicado: (2021)

The spoils of Poynton /
por: James, Henry, 1843-1916
Publicado: (1971)

The Scent of Spoils
Publicado: (1896)

The Spoils-system
Publicado: (1896)

Editorial: Clinical Paths for Soluble Epoxide Hydrolase Inhibitors
por: Imig, John D., et al.
Publicado: (2020)

The spoils of war and the long-term spoiling of health conditions of entire nations
por: Navarese, Eliano P., et al.
Publicado: (2022)

Herpes spoils excitement
por: Dove, Alan W.
Publicado: (2002)

Tuberculosis - The spoil sport
por: Govindarajan, MJ, et al.
Publicado: (2008)

Reply to: "The spoils of war and the long-term spoiling of health conditions of entire nations"
por: Keebayoon, Amnuay, et al.
Publicado: (2022)

Effects of Individual Circulating FFAs on Plasma and Hepatic FFA Epoxides, Diols, and Epoxide-Diol Ratios as Indices of Soluble Epoxide Hydrolase Activity
por: Oh, Young Taek, et al.
Publicado: (2023)

Colección Ren Bonian

Soluble Epoxide Hydrolase in Atherosclerosis
por: Wang, Yi-Xin Jim, et al.
Publicado: (2010)

Isovolumic loading of the failing heart by intraventricular placement of a spring expander attenuates cardiac atrophy after heterotopic heart transplantation
por: Pokorný, Martin, et al.
Publicado: (2018)

THE EFFECTS OF SUBMINIMUM DOSES OF STRYCHNINE IN NEPHRECTOMIZED RABBITS
por: Meltzer, S. J., et al.
Publicado: (1902)

Spare the Mbl, spoil the rod?
por: LeBrasseur, Nicole
Publicado: (2003)

What spoiled the CERN party
Publicado: (2009)

The Poisonous Principle of Spoiled Corn
Publicado: (1876)

Urinary Tract Abscess in Nephrectomized Renal Transplant Recipient
por: Afshar, Reza, et al.
Publicado: (2009)

HISS: Snakemake-based workflows for performing SMRT-RenSeq assembly, AgRenSeq and dRenSeq for the discovery of novel plant disease resistance genes
por: Adams, Thomas M., et al.
Publicado: (2023)

What Becomes of Some Spoiled Drugs
Publicado: (1899)

Ren Zhengfei: lessons from battle
por: Yu, Zhang
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_osprj426unq4p4q0no20ba2bpf