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Light‐Activated Translation of Different mRNAs in Cells via Wavelength‐Dependent Photouncaging

The 5′ cap is a hallmark of eukaryotic mRNA involved in the initiation of translation. Its modification with a single photo‐cleavable group can bring translation of mRNA under the control of light. However, UV irradiation causes cell stress and downregulation of translation. Furthermore, complex pro...

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Detalles Bibliográficos
Autores principales: Bollu, Amarnath, Klöcker, Nils, Špaček, Petr, P. Weissenboeck, Florian, Hüwel, Sabine, Rentmeister, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107135/
https://www.ncbi.nlm.nih.gov/pubmed/36417319
http://dx.doi.org/10.1002/anie.202209975