A randomized phase 2b efficacy study in patients with seizure episodes with a predictable pattern using Staccato® alprazolam for rapid seizure termination

OBJECTIVE: Alprazolam administered via the Staccato® breath‐actuated device is delivered into the deep lung for rapid systemic exposure and is a potential therapy for rapid epileptic seizure termination (REST). We conducted an inpatient study (ENGAGE‐E‐001 [NCT03478982]) in patients with stereotypic...

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Detalles Bibliográficos
Autores principales: French, Jacqueline, Biton, Victor, Dave, Hina, Detyniecki, Kamil, Gelfand, Michael A., Gong, Hui, Liow, Kore, O'Brien, Terence J., Sadek, Ahmed, DiVentura, Bree, Reich, Brittany, Isojarvi, Jouko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107237/
https://www.ncbi.nlm.nih.gov/pubmed/36268811
http://dx.doi.org/10.1111/epi.17441

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