Toll‐like receptors control the accumulation of neutrophils in lymph nodes that expand CD4(+) T cells during experimental autoimmune encephalomyelitis

Toll‐like receptors (TLR) control the activation of dendritic cells that prime CD4(+) T cells in draining lymph nodes, where these T cells then undergo massive clonal expansion. The mechanisms controlling this clonal T cell expansion are poorly defined. Using the CD4(+) T cell‐mediated disease exper...

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Detalles Bibliográficos
Autores principales: Shen, Ping, Rother, Madlen, Stervbo, Ulrik, Lampropoulou, Vicky, Calderon‐Gomez, Elisabeth, Roch, Toralf, Hilgenberg, Ellen, Ries, Steffi, Kühl, Anja A., Jouneau, Luc, Boudinot, Pierre, Fillatreau, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Immunodeficiencies and autoimmunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107244/
https://www.ncbi.nlm.nih.gov/pubmed/36458588
http://dx.doi.org/10.1002/eji.202250059

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