The tumor microenvironment drives NK cell metabolic dysfunction leading to impaired antitumor activity

NK cells represent key players capable of driving antitumor immune responses. However, the potent immunosuppressive activity of the tumor microenvironment (TME) may impair their effector function. Here, we strengthen the importance of metabolic interactions between NK cells and TME and propose metab...

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Detalles Bibliográficos
Autores principales: Tumino, Nicola, Nava Lauson, Carina B., Tiberti, Silvia, Besi, Francesca, Martini, Stefania, Fiore, Piera Filomena, Scodamaglia, Francesca, Mingari, Maria Cristina, Moretta, Lorenzo, Manzo, Teresa, Vacca, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Tumor Markers and Signatures
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107325/
https://www.ncbi.nlm.nih.gov/pubmed/36468179
http://dx.doi.org/10.1002/ijc.34389

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