Caging of a Strongly Pairing Fluorescent Thymidine Analog with Soft Nucleophiles

Controlling the pairing strength of nucleobases in DNA through reactions with compounds found inside the cell is a formidable challenge. Here we report how a thiazolyl substituent turns a strongly pairing ethynylpyridone C‐nucleoside into a reactive residue in oligonucleotides. The thiazolyl‐bearing...

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Detalles Bibliográficos
Autores principales: Eyberg, Juri, Ringenberg, Mark, Richert, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107337/
https://www.ncbi.nlm.nih.gov/pubmed/36395348
http://dx.doi.org/10.1002/chem.202203289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107337/
https://www.ncbi.nlm.nih.gov/pubmed/36395348
http://dx.doi.org/10.1002/chem.202203289

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