Justification of empiric methodology to determine dexmedetomidine dose for the TREX study

INTRODUCTION: Dexmedetomidine is the sedative agent administered in combination with remifentanil and low dose of sevoflurane in the interventional arm of the ongoing TREX trial (Trial Remifentanil DExmedetomidine). The TREX pilot study (published in Paediatr Anaesth 2019;29:59–67) established infus...

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Detalles Bibliográficos
Autores principales: Disma, Nicola, Goffredo, Bianca M., Cairoli, Sara, Cirillo, Ginevra, Morse, James, Anderson, Brian J., Bonfiglio, Rachele, Cordani, Ramona, Garrone, Marco, Patrone, Elisa, Iengo, Annalisa, Bocca, Paola, Izzo, Francesca, Diotto, Veronica, Lenares, Elena, Robino, Chiara, Neri, Simona, Colantonio, Laura, Calderini, Edoardo, Picardo, Sergio, Tucci, Isabella, Di Persio, Alessandra, Montagnini, Luigi, Blesi, Luca, Pistone, Barbara, Kuppers, Beate, De Lorenzo, Brita, Caramelli, Fabio, Pasini, Lorena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107467/
https://www.ncbi.nlm.nih.gov/pubmed/36398423
http://dx.doi.org/10.1111/pan.14605

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