Development of resistance to FGFR inhibition in urothelial carcinoma via multiple pathways in vitro

Alterations of fibroblast growth factor receptors (FGFRs) are common in bladder and other cancers and result in disrupted signalling via several pathways. Therapeutics that target FGFRs have now entered the clinic, but, in common with many cancer therapies, resistance develops in most cases. To mode...

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Detalles Bibliográficos
Autores principales: Pettitt, Geoffrey A, Hurst, Carolyn D, Khan, Zubeda, McPherson, Helen R, Dunning, Matthew C, Alder, Olivia, Platt, Fiona M, Black, Emma VI, Burns, Julie E, Knowles, Margaret A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107504/
https://www.ncbi.nlm.nih.gov/pubmed/36385700
http://dx.doi.org/10.1002/path.6034

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