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Genetically engineered multicistronic allele of Pmel yielding highly specific CreERT2‐mediated recombination in the melanocyte lineage

Genetic approaches that allow lineage tracing are essential to our future understanding of melanocytes and melanoma. To date, the approaches used to label melanocytes in mice have relied on random integration of transgenes driven by the promoters of the Tyrosinase and Dopachrome tautomerase genes, k...

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Detalles Bibliográficos
Autores principales: Wilkinson, Emma L., Brennan, Louise C., Harrison, Olivia J., Crane‐Smith, Zoe, Gautier, Philippe, Keighren, Margaret A., Budd, Peter, Swaminathan, Karthic, Machesky, Laura M., Allinson, Sarah L., Jackson, Ian J., Mort, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107733/
https://www.ncbi.nlm.nih.gov/pubmed/36412082
http://dx.doi.org/10.1111/pcmr.13076