A Randomized, Placebo‐Controlled Study of Methotrexate to Increase Response Rates in Patients with Uncontrolled Gout Receiving Pegloticase: Primary Efficacy and Safety Findings

OBJECTIVE: To assess efficacy, safety, pharmacokinetics, and immunogenicity of pegloticase plus methotrexate (MTX) versus pegloticase plus placebo cotreatment for uncontrolled gout in a randomized, placebo‐controlled, double‐blind trial. METHODS: This study included adults with uncontrolled gout, de...

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Detalles Bibliográficos
Autores principales: Botson, John K., Saag, Kenneth, Peterson, Jeff, Parikh, Naval, Ong, Stephen, La, Dan, LoCicero, Karon, Obermeyer, Katie, Xin, Yan, Chamberlain, Jason, LaMoreaux, Brian, Verma, Supra, Sainati, Stephen, Grewal, Suneet, Majjhoo, Amar, Tesser, John R. P., Weinblatt, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2022
Materias:
Gout
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107774/
https://www.ncbi.nlm.nih.gov/pubmed/36099211
http://dx.doi.org/10.1002/art.42335

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