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Going Viral: An Investigation into the Chameleonic Behaviour of Antiviral Compounds

The ability to adjust conformations in response to the polarity of the environment, i.e. molecular chameleonicity, is considered to be important for conferring both high aqueous solubility and high cell permeability to drugs in chemical space beyond Lipinski's rule of 5. We determined the confo...

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Detalles Bibliográficos
Autores principales:	Wieske, Lianne H. E., Atilaw, Yoseph, Poongavanam, Vasanthanathan, Erdélyi, Máté, Kihlberg, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107787/ https://www.ncbi.nlm.nih.gov/pubmed/36286339 http://dx.doi.org/10.1002/chem.202202798

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