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Diastereo‐ and Enantioselective Reductive Mannich‐type Reaction of α,β‐Unsaturated Carboxylic Acids to Ketimines: A Direct Entry to Unprotected β (2,3,3)‐Amino Acids

Stereoselective construction of unprotected β‐amino acids is a significant challenge owing to the lack of methods for the catalytic generation of highly enantioenriched carboxylic acid enolates. In this study, a novel copper‐catalyzed diastereo‐ and enantioselective reductive Mannich‐type reaction o...

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Detalles Bibliográficos
Autores principales:	Suzuki, Hirotsugu, Kondo, Sora, Yamada, Koichiro, Matsuda, Takanori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107894/ https://www.ncbi.nlm.nih.gov/pubmed/36341524 http://dx.doi.org/10.1002/chem.202202575

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