RAfilter: an algorithm for detecting and filtering false-positive alignments in repetitive genomic regions

Telomere to telomere (T2T) assembly relies on the correctness of sequence alignments. However, the existing aligners tend to generate a high proportion of false-positive alignments in repetitive genomic regions which impedes the generation of T2T-level reference genomes for more important species. I...

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Detalles Bibliográficos
Autores principales: Yang, Jinbao, Zhao, Xianjia, Jiang, Heling, Yang, Yingxue, Hou, Yuze, Pan, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107899/
https://www.ncbi.nlm.nih.gov/pubmed/37077372
http://dx.doi.org/10.1093/hr/uhac288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107899/
https://www.ncbi.nlm.nih.gov/pubmed/37077372
http://dx.doi.org/10.1093/hr/uhac288

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