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RAfilter: an algorithm for detecting and filtering false-positive alignments in repetitive genomic regions
Telomere to telomere (T2T) assembly relies on the correctness of sequence alignments. However, the existing aligners tend to generate a high proportion of false-positive alignments in repetitive genomic regions which impedes the generation of T2T-level reference genomes for more important species. I...
Autores principales: | Yang, Jinbao, Zhao, Xianjia, Jiang, Heling, Yang, Yingxue, Hou, Yuze, Pan, Weihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107899/ https://www.ncbi.nlm.nih.gov/pubmed/37077372 http://dx.doi.org/10.1093/hr/uhac288 |
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