Cargando…

Spontaneous hepatic haemorrhage after caesarean section in a patient with uraemia and superimposed preeclampsia: a case report

Perinatal spontaneous hepatic haemorrhage is a very rare disease affecting pregnant women, particularly those on long-term dialysis, that has a high maternal and infant mortality rate. Most patients experience preeclampsia with haemolysis, elevated liver enzymes and low platelets syndrome. Here, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yuanyuan, Liu, Kai, Song, Kangjie, Fang, Changtai, Zhu, Lianghua, Wu, Gaofei, Zha, Junjing, Zha, Jiaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107969/
https://www.ncbi.nlm.nih.gov/pubmed/37032603
http://dx.doi.org/10.1177/03000605231166510
_version_ 1785026726382796800
author Chen, Yuanyuan
Liu, Kai
Song, Kangjie
Fang, Changtai
Zhu, Lianghua
Wu, Gaofei
Zha, Junjing
Zha, Jiaan
author_facet Chen, Yuanyuan
Liu, Kai
Song, Kangjie
Fang, Changtai
Zhu, Lianghua
Wu, Gaofei
Zha, Junjing
Zha, Jiaan
author_sort Chen, Yuanyuan
collection PubMed
description Perinatal spontaneous hepatic haemorrhage is a very rare disease affecting pregnant women, particularly those on long-term dialysis, that has a high maternal and infant mortality rate. Most patients experience preeclampsia with haemolysis, elevated liver enzymes and low platelets syndrome. Here, the case of a 35-year-old multigravida patient with known chronic kidney disease and chronic hypertension with uraemia, who developed spontaneous hepatic haemorrhage after caesarean section, is described. The patient experienced sudden massive circulatory failure, but hemodynamics were temporarily stabilized after emergency surgery. Following transfer to the intensive care unit for continued treatment, her blood pressure and haemoglobin level continued to drop. Selective hepatic artery embolization was performed on day 2 after delivery, and her vital signs gradually stabilized. On day 30 after delivery, the patient was discharged in a stable condition. The newborn recovered after therapy in neonatal intensive care for 2 months. The present case suggests that, for perinatal spontaneous hepatic haemorrhage, timely and accurate diagnosis, multidisciplinary management and determining the therapeutic approach according to clinical symptoms are essential.
format Online
Article
Text
id pubmed-10107969
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-101079692023-04-18 Spontaneous hepatic haemorrhage after caesarean section in a patient with uraemia and superimposed preeclampsia: a case report Chen, Yuanyuan Liu, Kai Song, Kangjie Fang, Changtai Zhu, Lianghua Wu, Gaofei Zha, Junjing Zha, Jiaan J Int Med Res Case Reports Perinatal spontaneous hepatic haemorrhage is a very rare disease affecting pregnant women, particularly those on long-term dialysis, that has a high maternal and infant mortality rate. Most patients experience preeclampsia with haemolysis, elevated liver enzymes and low platelets syndrome. Here, the case of a 35-year-old multigravida patient with known chronic kidney disease and chronic hypertension with uraemia, who developed spontaneous hepatic haemorrhage after caesarean section, is described. The patient experienced sudden massive circulatory failure, but hemodynamics were temporarily stabilized after emergency surgery. Following transfer to the intensive care unit for continued treatment, her blood pressure and haemoglobin level continued to drop. Selective hepatic artery embolization was performed on day 2 after delivery, and her vital signs gradually stabilized. On day 30 after delivery, the patient was discharged in a stable condition. The newborn recovered after therapy in neonatal intensive care for 2 months. The present case suggests that, for perinatal spontaneous hepatic haemorrhage, timely and accurate diagnosis, multidisciplinary management and determining the therapeutic approach according to clinical symptoms are essential. SAGE Publications 2023-04-09 /pmc/articles/PMC10107969/ /pubmed/37032603 http://dx.doi.org/10.1177/03000605231166510 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Reports
Chen, Yuanyuan
Liu, Kai
Song, Kangjie
Fang, Changtai
Zhu, Lianghua
Wu, Gaofei
Zha, Junjing
Zha, Jiaan
Spontaneous hepatic haemorrhage after caesarean section in a patient with uraemia and superimposed preeclampsia: a case report
title Spontaneous hepatic haemorrhage after caesarean section in a patient with uraemia and superimposed preeclampsia: a case report
title_full Spontaneous hepatic haemorrhage after caesarean section in a patient with uraemia and superimposed preeclampsia: a case report
title_fullStr Spontaneous hepatic haemorrhage after caesarean section in a patient with uraemia and superimposed preeclampsia: a case report
title_full_unstemmed Spontaneous hepatic haemorrhage after caesarean section in a patient with uraemia and superimposed preeclampsia: a case report
title_short Spontaneous hepatic haemorrhage after caesarean section in a patient with uraemia and superimposed preeclampsia: a case report
title_sort spontaneous hepatic haemorrhage after caesarean section in a patient with uraemia and superimposed preeclampsia: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107969/
https://www.ncbi.nlm.nih.gov/pubmed/37032603
http://dx.doi.org/10.1177/03000605231166510
work_keys_str_mv AT chenyuanyuan spontaneoushepatichaemorrhageaftercaesareansectioninapatientwithuraemiaandsuperimposedpreeclampsiaacasereport
AT liukai spontaneoushepatichaemorrhageaftercaesareansectioninapatientwithuraemiaandsuperimposedpreeclampsiaacasereport
AT songkangjie spontaneoushepatichaemorrhageaftercaesareansectioninapatientwithuraemiaandsuperimposedpreeclampsiaacasereport
AT fangchangtai spontaneoushepatichaemorrhageaftercaesareansectioninapatientwithuraemiaandsuperimposedpreeclampsiaacasereport
AT zhulianghua spontaneoushepatichaemorrhageaftercaesareansectioninapatientwithuraemiaandsuperimposedpreeclampsiaacasereport
AT wugaofei spontaneoushepatichaemorrhageaftercaesareansectioninapatientwithuraemiaandsuperimposedpreeclampsiaacasereport
AT zhajunjing spontaneoushepatichaemorrhageaftercaesareansectioninapatientwithuraemiaandsuperimposedpreeclampsiaacasereport
AT zhajiaan spontaneoushepatichaemorrhageaftercaesareansectioninapatientwithuraemiaandsuperimposedpreeclampsiaacasereport