Increased uptake of the P2X7 receptor radiotracer (18)F‐JNJ‐64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice

OBJECTIVE: The P2X7 receptor (P2X7R) is an important contributor to neuroinflammation, responding to extracellularly released adenosine triphosphate. Expression of the P2X7R is increased in the brain in experimental and human epilepsy, and genetic or pharmacologic targeting of the receptor can reduc...

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Detalles Bibliográficos
Autores principales: Morgan, James, Moreno, Oscar, Alves, Mariana, Baz, Zuriñe, Menéndez Méndez, Aida, Leister, Hanna, Melia, Ciara, Smith, Jonathon, Visekruna, Alexander, Nicke, Annette, Bhattacharya, Anindya, Ceusters, Marc, Henshall, David C., Gómez‐Vallejo, Vanessa, Llop, Jordi, Engel, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108015/
https://www.ncbi.nlm.nih.gov/pubmed/36507708
http://dx.doi.org/10.1111/epi.17484

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