Cargando…
Semi‐supervised clustering of quaternion time series: Application to gait analysis in multiple sclerosis using motion sensor data
Recent approaches in gait analysis involve the use of wearable motion sensors to extract spatio‐temporal parameters that characterize multiple aspects of an individual's gait. In particular, the medical community could largely benefit from this type of devices as they could provide the clinicia...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108058/ https://www.ncbi.nlm.nih.gov/pubmed/36509423 http://dx.doi.org/10.1002/sim.9625 |
_version_ | 1785026760154284032 |
---|---|
author | Drouin, Pierre Stamm, Aymeric Chevreuil, Laurent Graillot, Vincent Barbin, Laetitia Gourraud, Pierre‐Antoine Laplaud, David‐Axel Bellanger, Lise |
author_facet | Drouin, Pierre Stamm, Aymeric Chevreuil, Laurent Graillot, Vincent Barbin, Laetitia Gourraud, Pierre‐Antoine Laplaud, David‐Axel Bellanger, Lise |
author_sort | Drouin, Pierre |
collection | PubMed |
description | Recent approaches in gait analysis involve the use of wearable motion sensors to extract spatio‐temporal parameters that characterize multiple aspects of an individual's gait. In particular, the medical community could largely benefit from this type of devices as they could provide the clinicians with a valuable tool for assessing gait impairment. Motion sensor data are however complex and there is an urgent unmet need to develop sound statistical methods for analyzing such data and extracting clinically relevant information. In this article, we measure gait by following the hip rotation over time and the resulting statistical unit is a time series of unit quaternions. We explore the possibility to form groups of patients with similar walking impairment by taking into account their walking data and their global decease severity with semi‐supervised clustering. We generalize a compromise‐based method named hclustcompro to unit quaternion time series by combining it with the proper dissimilarity quaternion dynamic time warping. We apply this method on patients diagnosed with multiple sclerosis to form groups of patients with similar walking deficiencies while accounting for the clinical assessment of their overall disability. We also compare the compromise‐based clustering approach with the method mergeTrees that falls into a sub‐class of ensemble clustering named collaborative clustering. The results provide a first proof of both the interest of using wearable motion sensors for assessing gait impairment and the use of prior knowledge to guide the clustering process. It also demonstrates that compromise‐based clustering is a more appropriate approach in this context. |
format | Online Article Text |
id | pubmed-10108058 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-101080582023-04-18 Semi‐supervised clustering of quaternion time series: Application to gait analysis in multiple sclerosis using motion sensor data Drouin, Pierre Stamm, Aymeric Chevreuil, Laurent Graillot, Vincent Barbin, Laetitia Gourraud, Pierre‐Antoine Laplaud, David‐Axel Bellanger, Lise Stat Med Research Articles Recent approaches in gait analysis involve the use of wearable motion sensors to extract spatio‐temporal parameters that characterize multiple aspects of an individual's gait. In particular, the medical community could largely benefit from this type of devices as they could provide the clinicians with a valuable tool for assessing gait impairment. Motion sensor data are however complex and there is an urgent unmet need to develop sound statistical methods for analyzing such data and extracting clinically relevant information. In this article, we measure gait by following the hip rotation over time and the resulting statistical unit is a time series of unit quaternions. We explore the possibility to form groups of patients with similar walking impairment by taking into account their walking data and their global decease severity with semi‐supervised clustering. We generalize a compromise‐based method named hclustcompro to unit quaternion time series by combining it with the proper dissimilarity quaternion dynamic time warping. We apply this method on patients diagnosed with multiple sclerosis to form groups of patients with similar walking deficiencies while accounting for the clinical assessment of their overall disability. We also compare the compromise‐based clustering approach with the method mergeTrees that falls into a sub‐class of ensemble clustering named collaborative clustering. The results provide a first proof of both the interest of using wearable motion sensors for assessing gait impairment and the use of prior knowledge to guide the clustering process. It also demonstrates that compromise‐based clustering is a more appropriate approach in this context. John Wiley & Sons, Inc. 2022-12-12 2023-02-20 /pmc/articles/PMC10108058/ /pubmed/36509423 http://dx.doi.org/10.1002/sim.9625 Text en © 2022 The Authors. Statistics in Medicine published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Research Articles Drouin, Pierre Stamm, Aymeric Chevreuil, Laurent Graillot, Vincent Barbin, Laetitia Gourraud, Pierre‐Antoine Laplaud, David‐Axel Bellanger, Lise Semi‐supervised clustering of quaternion time series: Application to gait analysis in multiple sclerosis using motion sensor data |
title | Semi‐supervised clustering of quaternion time series: Application to gait analysis in multiple sclerosis using motion sensor data |
title_full | Semi‐supervised clustering of quaternion time series: Application to gait analysis in multiple sclerosis using motion sensor data |
title_fullStr | Semi‐supervised clustering of quaternion time series: Application to gait analysis in multiple sclerosis using motion sensor data |
title_full_unstemmed | Semi‐supervised clustering of quaternion time series: Application to gait analysis in multiple sclerosis using motion sensor data |
title_short | Semi‐supervised clustering of quaternion time series: Application to gait analysis in multiple sclerosis using motion sensor data |
title_sort | semi‐supervised clustering of quaternion time series: application to gait analysis in multiple sclerosis using motion sensor data |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108058/ https://www.ncbi.nlm.nih.gov/pubmed/36509423 http://dx.doi.org/10.1002/sim.9625 |
work_keys_str_mv | AT drouinpierre semisupervisedclusteringofquaterniontimeseriesapplicationtogaitanalysisinmultiplesclerosisusingmotionsensordata AT stammaymeric semisupervisedclusteringofquaterniontimeseriesapplicationtogaitanalysisinmultiplesclerosisusingmotionsensordata AT chevreuillaurent semisupervisedclusteringofquaterniontimeseriesapplicationtogaitanalysisinmultiplesclerosisusingmotionsensordata AT graillotvincent semisupervisedclusteringofquaterniontimeseriesapplicationtogaitanalysisinmultiplesclerosisusingmotionsensordata AT barbinlaetitia semisupervisedclusteringofquaterniontimeseriesapplicationtogaitanalysisinmultiplesclerosisusingmotionsensordata AT gourraudpierreantoine semisupervisedclusteringofquaterniontimeseriesapplicationtogaitanalysisinmultiplesclerosisusingmotionsensordata AT laplauddavidaxel semisupervisedclusteringofquaterniontimeseriesapplicationtogaitanalysisinmultiplesclerosisusingmotionsensordata AT bellangerlise semisupervisedclusteringofquaterniontimeseriesapplicationtogaitanalysisinmultiplesclerosisusingmotionsensordata |