Memory CD8(+) T cells upregulate glycolysis and effector functions under limiting oxygen conditions

Memory CD8(+) T cells are indispensable for maintaining long‐term immunity against intracellular pathogens and tumors. Despite their presence at oxygen‐deprived infected tissue sites or in tumors, the impact of local oxygen pressure on memory CD8(+) T cells remains largely unclear. We sought to eluc...

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Detalles Bibliográficos
Autores principales: Beumer‐Chuwonpad, Ammarina, van Alphen, Floris P.J., Kragten, Natasja A.M., Freen‐van Heeren, Julian J., Rodriguez Gomez, Maria, Verhoeven, Arthur J., van den Biggelaar, Maartje, van Gisbergen, Klaas P.J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Adaptive immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108084/
https://www.ncbi.nlm.nih.gov/pubmed/36482267
http://dx.doi.org/10.1002/eji.202249918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108084/
https://www.ncbi.nlm.nih.gov/pubmed/36482267
http://dx.doi.org/10.1002/eji.202249918

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