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Evidence for etiologic field changes in tongue distant from tumor in patients with squamous cell carcinoma of the oral tongue

Oral cancer is a paradigm of Slaughter's concept of field cancerization, where tumors are thought to originate within an area of cells containing genetic alterations that predispose to cancer development. The field size is unclear but may represent a large area of tissue, and the origin of muta...

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Detalles Bibliográficos
Autores principales: Gu, Xiaolian, Wang, Lixiao, Coates, Philip J, Gnanasundram, Sivakumar Vadivel, Sgaramella, Nicola, Sörlin, Jonas, Erdogan, Baris, Magan, Mustafa, Nylander, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108103/
https://www.ncbi.nlm.nih.gov/pubmed/36314576
http://dx.doi.org/10.1002/path.6025