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Evidence for etiologic field changes in tongue distant from tumor in patients with squamous cell carcinoma of the oral tongue
Oral cancer is a paradigm of Slaughter's concept of field cancerization, where tumors are thought to originate within an area of cells containing genetic alterations that predispose to cancer development. The field size is unclear but may represent a large area of tissue, and the origin of muta...
Autores principales: | Gu, Xiaolian, Wang, Lixiao, Coates, Philip J, Gnanasundram, Sivakumar Vadivel, Sgaramella, Nicola, Sörlin, Jonas, Erdogan, Baris, Magan, Mustafa, Nylander, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108103/ https://www.ncbi.nlm.nih.gov/pubmed/36314576 http://dx.doi.org/10.1002/path.6025 |
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