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Actinorhodin Biosynthesis Terminates with an Unprecedented Biaryl Coupling Reaction

A plethora of dimeric natural products exist with diverse chemical structures and biological activities. A major strategy for dimerization is aryl coupling catalyzed by cytochrome P450 or laccase. Actinorhodin (ACT) from Streptomyces coelicolor A3(2) has a dimeric pyranonaphthoquinone structure conn...

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Detalles Bibliográficos
Autores principales:	Hashimoto, Makoto, Watari, Susumu, Taguchi, Takaaki, Ishikawa, Kazuki, Kumamoto, Takuya, Okamoto, Susumu, Ichinose, Koji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108166/ https://www.ncbi.nlm.nih.gov/pubmed/36460615 http://dx.doi.org/10.1002/anie.202214400

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