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Enantioselective CE–MS analysis of ketamine metabolites in urine

The chiral drug ketamine has long‐lasting antidepressant effects with a fast onset and is also suitable to treat patients with therapy‐resistant depression. The metabolite hydroxynorketamine (HNK) plays an important role in the antidepressant mechanism of action. Hydroxylation at the cyclohexanone r...

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Detalles Bibliográficos
Autores principales:	Sandbaumhüter, Friederike A., Aerts, Jordan T., Theurillat, Regula, Andrén, Per E., Thormann, Wolfgang, Jansson, Erik T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	General, Ce & Cec
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108174/ https://www.ncbi.nlm.nih.gov/pubmed/36398998 http://dx.doi.org/10.1002/elps.202200175

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