Cargando…
Low‐dose dexamethasone promotes osteoblast viability by activating autophagy via the SGK1/FOXO3a signaling pathway
Autophagy contributes to bone homeostasis and development under physiological conditions. Although previous studies have demonstrated the induction of the autophagy machinery by endogenous glucocorticoids (GCs), the precise mechanisms involved have not yet been clarified. The current study aimed to...
Autores principales: | Yu, Xiang‐Hua, Xu, Xiao‐Ming, Zhang, Sheng‐Xiang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108317/ https://www.ncbi.nlm.nih.gov/pubmed/36453461 http://dx.doi.org/10.1002/cbin.11971 |
Ejemplares similares
-
Low-dose dexamethasone affects osteoblast viability by inducing autophagy via intracellular ROS
por: Zhang, Shaokun, et al.
Publicado: (2018) -
SGK1 inhibition induces autophagy-dependent apoptosis via the mTOR-Foxo3a pathway
por: Liu, Weiwei, et al.
Publicado: (2017) -
Dose-dependent inhibitory effects of zoledronic acid on osteoblast viability and function in vitro
por: HUANG, XIN, et al.
Publicado: (2016) -
Dexamethasone enhances the lung metastasis of breast cancer via a PI3K-SGK1-CTGF pathway
por: Zhang, Yujing, et al.
Publicado: (2021) -
SGK1 Inhibits Autophagy in Murine Muscle Tissue
por: Zuleger, Theresia, et al.
Publicado: (2018)