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Oldie but Goodie: Is Technetium-99m Still a Treasure Trove of Innovation for Medicine? A Patents Analysis (2000–2022)

[Image: see text] Technetium-99m is the workhorse of diagnostic nuclear medicine. The aim of the work is to analyze the technetium-99m patents since 2000 to photograph its innovation. QUESTEL’s ORBIT Intelligence system was used for the collection of technetium inventions disclosed in patents and pa...

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Autores principales: Riondato, Mattia, Rigamonti, Dorotea, Martini, Petra, Cittanti, Corrado, Boschi, Alessandra, Urso, Luca, Uccelli, Licia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108350/
https://www.ncbi.nlm.nih.gov/pubmed/37010457
http://dx.doi.org/10.1021/acs.jmedchem.3c00148
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author Riondato, Mattia
Rigamonti, Dorotea
Martini, Petra
Cittanti, Corrado
Boschi, Alessandra
Urso, Luca
Uccelli, Licia
author_facet Riondato, Mattia
Rigamonti, Dorotea
Martini, Petra
Cittanti, Corrado
Boschi, Alessandra
Urso, Luca
Uccelli, Licia
author_sort Riondato, Mattia
collection PubMed
description [Image: see text] Technetium-99m is the workhorse of diagnostic nuclear medicine. The aim of the work is to analyze the technetium-99m patents since 2000 to photograph its innovation. QUESTEL’s ORBIT Intelligence system was used for the collection of technetium inventions disclosed in patents and patent applications in more than 96 countries in the period 2000–2022; 2768 patent documents were analyzed. Patent counting and analysis have shown that SPECT imaging using technetium-99m radiopharmaceuticals is still robust. The introduction of new technetium-99m radiopharmaceuticals into clinical routine goes beyond successful trials. In eastern economies, such as China and other emerging markets, patent applications are on the rise, while those in developed western countries are stagnating, with some exceptions for the United States. But despite the difficulties, academic and industrial research on these tracers remains essential for the development of nuclear medicine.
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spelling pubmed-101083502023-04-18 Oldie but Goodie: Is Technetium-99m Still a Treasure Trove of Innovation for Medicine? A Patents Analysis (2000–2022) Riondato, Mattia Rigamonti, Dorotea Martini, Petra Cittanti, Corrado Boschi, Alessandra Urso, Luca Uccelli, Licia J Med Chem [Image: see text] Technetium-99m is the workhorse of diagnostic nuclear medicine. The aim of the work is to analyze the technetium-99m patents since 2000 to photograph its innovation. QUESTEL’s ORBIT Intelligence system was used for the collection of technetium inventions disclosed in patents and patent applications in more than 96 countries in the period 2000–2022; 2768 patent documents were analyzed. Patent counting and analysis have shown that SPECT imaging using technetium-99m radiopharmaceuticals is still robust. The introduction of new technetium-99m radiopharmaceuticals into clinical routine goes beyond successful trials. In eastern economies, such as China and other emerging markets, patent applications are on the rise, while those in developed western countries are stagnating, with some exceptions for the United States. But despite the difficulties, academic and industrial research on these tracers remains essential for the development of nuclear medicine. American Chemical Society 2023-04-03 /pmc/articles/PMC10108350/ /pubmed/37010457 http://dx.doi.org/10.1021/acs.jmedchem.3c00148 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Riondato, Mattia
Rigamonti, Dorotea
Martini, Petra
Cittanti, Corrado
Boschi, Alessandra
Urso, Luca
Uccelli, Licia
Oldie but Goodie: Is Technetium-99m Still a Treasure Trove of Innovation for Medicine? A Patents Analysis (2000–2022)
title Oldie but Goodie: Is Technetium-99m Still a Treasure Trove of Innovation for Medicine? A Patents Analysis (2000–2022)
title_full Oldie but Goodie: Is Technetium-99m Still a Treasure Trove of Innovation for Medicine? A Patents Analysis (2000–2022)
title_fullStr Oldie but Goodie: Is Technetium-99m Still a Treasure Trove of Innovation for Medicine? A Patents Analysis (2000–2022)
title_full_unstemmed Oldie but Goodie: Is Technetium-99m Still a Treasure Trove of Innovation for Medicine? A Patents Analysis (2000–2022)
title_short Oldie but Goodie: Is Technetium-99m Still a Treasure Trove of Innovation for Medicine? A Patents Analysis (2000–2022)
title_sort oldie but goodie: is technetium-99m still a treasure trove of innovation for medicine? a patents analysis (2000–2022)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108350/
https://www.ncbi.nlm.nih.gov/pubmed/37010457
http://dx.doi.org/10.1021/acs.jmedchem.3c00148
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