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Conformational ensembles explain NMR spectra of frozen intrinsically disordered proteins

Protein regions which are intrinsically disordered, exist as an ensemble of rapidly interconverting structures. Cooling proteins to cryogenic temperatures for dynamic nuclear polarization (DNP) magic angle spinning (MAS) NMR studies suspends most of the motions, resulting in peaks that are broad but...

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Detalles Bibliográficos
Autores principales:	Kragelj, Jaka, Dumarieh, Rania, Xiao, Yiling, Frederick, Kendra K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2023
Materias:	Full‐length Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108432/ https://www.ncbi.nlm.nih.gov/pubmed/36930141 http://dx.doi.org/10.1002/pro.4628

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