DeepEdit: single-molecule detection and phasing of A-to-I RNA editing events using nanopore direct RNA sequencing

Single-molecule detection and phasing of A-to-I RNA editing events remain an unresolved problem. Long-read and PCR-free nanopore native RNA sequencing offers a great opportunity for direct RNA editing detection. Here, we develop a neural network model, DeepEdit, that not only recognizes A-to-I editi...

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Detalles Bibliográficos
Autores principales: Chen, Longxian, Ou, Liang, Jing, Xinyun, Kong, Yimeng, Xie, Bingran, Zhang, Niubing, Shi, Han, Qin, Hang, Li, Xuan, Hao, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108526/
https://www.ncbi.nlm.nih.gov/pubmed/37069604
http://dx.doi.org/10.1186/s13059-023-02921-0

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