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Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells
The ADP-ribosyltransferase PARP7 modulates protein function by conjugating ADP-ribose to the side chains of acceptor amino acids. PARP7 has been shown to affect gene expression in prostate cancer cells and certain other cell types by mechanisms that include transcription factor ADP-ribosylation. Her...
Autores principales: | Yang, Chunsong, Wierbiłowicz, Krzysztof, Dworak, Natalia M., Bae, Song Yi, Tengse, Sachi B., Abianeh, Nicki, Drake, Justin M., Abbas, Tarek, Ratan, Aakrosh, Wotton, David, Paschal, Bryce M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108886/ https://www.ncbi.nlm.nih.gov/pubmed/37077937 http://dx.doi.org/10.1158/2767-9764.CRC-23-0086 |
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