Cargando…

C9orf72 expansions are the most common cause of genetic frontotemporal dementia in a Southeast Asian cohort

OBJECTIVE: Frontotemporal dementia (FTD) encompasses a spectrum of neurodegenerative disorders, including behavioural variant FTD (bvFTD), semantic variant primary progressive aphasia (svPPA) and non‐fluent variant PPA (nfvPPA). While a strong genetic component is implicated in FTD, genetic FTD in A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tan, Yi Jayne, Yong, Alisa C. W., Foo, Jia Nee, Lian, Michelle M., Lim, Weng Khong, Dominguez, Jacqueline, Fong, Zhi Hui, Narasimhalu, Kaavya, Chiew, Hui Jin, Ng, Kok Pin, Ting, Simon K. S., Kandiah, Nagaendran, Ng, Adeline S. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109321/ https://www.ncbi.nlm.nih.gov/pubmed/36799407 http://dx.doi.org/10.1002/acn3.51744

Ejemplares similares

Frontotemporal Dementia in Southeast Asia: A Comparative Study
por: Tan, Yee-Leng, et al.
Publicado: (2013)

High Diagnostic Utility Incorporating a Targeted Neurodegeneration Gene Panel With MRI Brain Diagnostic Algorithms in Patients With Young-Onset Cognitive Impairment With Leukodystrophy
por: Chen, Zhiyong, et al.
Publicado: (2021)

Dementia in Southeast Asia: influence of onset-type, education, and cerebrovascular disease
por: Vipin, Ashwati, et al.
Publicado: (2021)

Frontotemporal dementia and COVID‐19: Hypothesis generation and roadmap for future research
por: Ng, Kok Pin, et al.
Publicado: (2021)

Altered Cerebrospinal Fluid Exosomal microRNA Levels in Young-Onset Alzheimer’s Disease and Frontotemporal Dementia
por: Tan, Yi Jayne, et al.
Publicado: (2021)

Associations of AT(N) biomarkers with neuropsychiatric symptoms in preclinical Alzheimer’s disease and cognitively unimpaired individuals
por: Ng, Kok Pin, et al.
Publicado: (2021)

Distinct network topology in Alzheimer’s disease and behavioral variant frontotemporal dementia
por: Ng, Adeline Su Lyn, et al.
Publicado: (2021)

Brain Metabolic Dysfunction in Early Neuropsychiatric Symptoms of Dementia
por: Ng, Kok Pin, et al.
Publicado: (2019)

A novel language-neutral Visual Cognitive Assessment Test (VCAT): validation in four Southeast Asian countries
por: Lim, Levinia, et al.
Publicado: (2018)

Assessment of psychiatric changes in C9ORF72 frontotemporal dementia
por: Hornberger, Michael
Publicado: (2012)

Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementia
por: Fratta, Pietro, et al.
Publicado: (2013)

Clinical Characteristics of C9ORF72-Linked Frontotemporal Lobar Degeneration
por: Kaivorinne, Anna-Lotta, et al.
Publicado: (2013)

Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration
por: Mizielinska, Sarah, et al.
Publicado: (2017)

Microglia in frontotemporal lobar degeneration with progranulin or C9ORF72 mutations
por: Sakae, Nobutaka, et al.
Publicado: (2019)

Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit
por: Sattler, Rita, et al.
Publicado: (2023)

Intermediate C9orf72 alleles in neurological disorders: does size really matter?
por: Ng, Adeline S L, et al.
Publicado: (2017)

Novel Optineurin Frameshift Insertion in a Family With Frontotemporal Dementia and Parkinsonism Without Amyotrophic Lateral Sclerosis
por: Dominguez, Jacqueline, et al.
Publicado: (2021)

Longitudinal neuroimaging and neuropsychological profiles of frontotemporal dementia with C9ORF72 expansions
por: Mahoney, Colin J, et al.
Publicado: (2012)

C9ORF72 Repeat Expansion in Australian and Spanish Frontotemporal Dementia Patients
por: Dobson-Stone, Carol, et al.
Publicado: (2013)

Altered body schema processing in frontotemporal dementia with C9ORF72 mutations
por: Downey, Laura E, et al.
Publicado: (2014)

Thalamic atrophy in frontotemporal dementia — Not just a C9orf72 problem
por: Bocchetta, Martina, et al.
Publicado: (2018)

Neuropsychiatric features of C9orf72-associated behavioral variant frontotemporal dementia and frontotemporal dementia with motor neuron disease
por: Takada, Leonel T, et al.
Publicado: (2012)

Amyloid-Tau-Neurodegeneration Profiles and Longitudinal Cognition in Sporadic Young-Onset Dementia
por: Vipin, Ashwati, et al.
Publicado: (2022)

Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics
por: Whitwell, Jennifer L., et al.
Publicado: (2012)

Impaired self-other differentiation in frontotemporal dementia due to the C9ORF72 expansion
por: Downey, Laura E, et al.
Publicado: (2012)

C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia: gain or loss of function?
por: Mizielinska, Sarah, et al.
Publicado: (2014)

The Development of C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Disorders
por: Yang, Qijie, et al.
Publicado: (2020)

Modeling C9orf72-Related Frontotemporal Dementia and Amyotrophic Lateral Sclerosis in Drosophila
por: Sharpe, Joanne L., et al.
Publicado: (2021)

Cortical iron accumulation in MAPT ‐ and C9orf 72‐associated frontotemporal lobar degeneration
por: Giannini, Lucia A. A., et al.
Publicado: (2023)

Role of Cognitive Enhancer Therapy in Alzheimer’s Disease with Concomitant Cerebral White Matter Disease: Findings from a Long-Term Naturalistic Study
por: Ng, Kok Pin, et al.
Publicado: (2014)

Reduced C9orf72 protein levels in frontal cortex of amyotrophic lateral sclerosis and frontotemporal degeneration brain with the C9ORF72 hexanucleotide repeat expansion()
por: Waite, Adrian J., et al.
Publicado: (2014)

Frontotemporal dementia with the C9ORF72 hexanucleotide repeat expansion: clinical, neuroanatomical and neuropathological features
por: Mahoney, Colin J., et al.
Publicado: (2012)

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking
por: Farg, Manal A., et al.
Publicado: (2014)

The neural correlates and clinical characteristics of psychosis in the frontotemporal dementia continuum and the C9orf72 expansion
por: Devenney, Emma M, et al.
Publicado: (2016)

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking
por: Farg, Manal A, et al.
Publicado: (2017)

Mechanisms of Immune Activation by c9orf72-Expansions in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
por: Trageser, Kyle J., et al.
Publicado: (2019)

Glial Cell Dysfunction in C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
por: Ghasemi, Mehdi, et al.
Publicado: (2021)

Serial position effects differ between Alzheimer’s and vascular features in mild cognitive impairment
por: Chander, Russell Jude, et al.
Publicado: (2018)

Characterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72
por: Boeve, Bradley F., et al.
Publicado: (2012)

C9orf72 frontotemporal lobar degeneration is characterised by frequent neuronal sense and antisense RNA foci
por: Mizielinska, Sarah, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_2u83ui2g02hcpj355ttlfin1l6