P007 CPAP implementation and its outcomes among Indigenous adult patients with OSA in the Top End Northern Territory of Australia

INTRODUCTION/AIM: Obstructive sleep apnoea (OSA) is reported to be highly prevalent among Indigenous Australians. However, the studies assessing the outcome of CPAP therapy among this population is sparsely reported. In this study we compared the polysomnographic (PSG) characteristic among Indigenous patients who underwent both diagnostic and continuous positive airway pressure (CPAP) implementation study in the Top End Northern Territory of Australia. METHODS: All adult Indigenous patients identified to have undergone both a diagnostic polysomnography followed by an in-lab CPAP implementation study were included. RESULTS: 145 patients (44% female) were included with a median age 49 years, and median BMI of 35 kg/m2. The OSA severity was - 5% mild, 26% moderate & 68% severe on the diagnostic sleep study. On application of CPAP the Total Arousal Index (diagnostic 28 to 16/hour on CPAP), Total Apnea Hypopnea Index (AHI) (diagnostic 48 to 8/hour on CPAP), Non-rapid eye movement (NREM) AHI (diagnostic 46 to 8/hour on CPAP), Rapid eye movement (REM) AHI (diagnostic 56 to 8/hour on CPAP) and SpO2 (diagnostic 93% to 95 % on CPAP) significantly improved. CONCLUSION: This study demonstrates that there is significant improvement in arousal Index, reduction in AHI both during NREM and REM sleep along with improvement in overall oxygen saturation upon application of CPAP among Indigenous patients with OSA. Hence, long term CPAP therapy should be offered/considered among Indigenous patients diagnosed to have OSA when clinically appropriate. GRANT SUPPORT: Nil to declare and no funding received for this study