Cargando…

O002 A novel, optogenetics based therapy for obstructive sleep apnea

INTRODUCTION: Many obstructive sleep apnea (OSA) patients are sub-optimally treated due to poor tolerance or incomplete response to established therapies. We propose a novel stimulation therapy that sensitises the dilator muscles to light activation (‘optogenetics') and activates the muscles wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Knapman, F, Cohen, M, Kulaga, T, Lisowski, L, Lovell, N, McMullan, S, Burke, P, Bilston, L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	ORAL PRESENTATIONS
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109414/ http://dx.doi.org/10.1093/sleepadvances/zpac029.001

Ejemplares similares

P063 Optogenetics for Obstructive Sleep Apnea
por: Knapman, F, et al.
Publicado: (2021)

O054 Genioglossus neural drive and upper airway dilation in people with obstructive sleep apnoea during wakefulness
por: Jugé, L, et al.
Publicado: (2022)

O027 Patterns of nocturnal swallow frequency and related tachycardia with sleep stages and obstructive sleep apnoea severity
por: Lin, A, et al.
Publicado: (2023)

O013 The pathogenesis of obstructive sleep apnea in individuals with comorbid insomnia and obstructive sleep apnoea (COMISA)
por: Brooker, E, et al.
Publicado: (2021)

O053 Obstructive sleep apnea is a distinct physiological phenotype in individuals with comorbid insomnia and sleep apnea (COMISA)
por: Brooker, E, et al.
Publicado: (2022)

O074 A systematic scoping review of minimally invasive respiratory monitoring
por: Bull, C, et al.
Publicado: (2022)

O057 The Impact of Surgical Weight Loss on the Physiological Endotypes causing Obstructive Sleep Apnea
por: Beatty, C, et al.
Publicado: (2023)

O001 Reboxetine reduces obstructive sleep apnea severity: a randomized trial
por: Altree, T, et al.
Publicado: (2021)

O029 Sleep architecture differs for individuals manifesting excessive daytime sleepiness with and without obstructive sleep apnea
por: Chen, X, et al.
Publicado: (2022)

Pharyngeal enlargement via tongue advancement differs with mandibular advancement therapy response and improves treatment prediction
por: Jugé, L, et al.
Publicado: (2021)

O025 Smart polymer implants as an emerging technology for treating airway collapse in obstructive sleep apnea: proof of concept
por: Sideris, A, et al.
Publicado: (2021)

O002 High strain evening exercise disrupts sleep: Insights from a real-world examination of ~7-million nights
por: Leota, J, et al.
Publicado: (2023)

O002 Medical therapy for sleep disordered breathing in children: a randomised, double-blind placebo-controlled trial
por: Baker, A, et al.
Publicado: (2021)

O028 Combination Pharmacological Therapy Targeting Multiple Mechanisms of Sleep Apnea
por: Sands, S, et al.
Publicado: (2022)

O002. Did Picasso and De Chirico really suffer from migraine auras?
por: Lisotto, Carlo, et al.
Publicado: (2015)

O043 Investigating Upper-Airway Mechanics with Computational Tongue Models
por: Lloyd, R, et al.
Publicado: (2023)

O055 Flow limitation and sleepiness in individuals without sleep apnea
por: Mann, D, et al.
Publicado: (2022)

O003 Longitudinal associations of obstructive sleep apnea and sleep macroarchitecture with future cognitive function in middle-aged and older men from a community-based cohort study
por: Parker, J, et al.
Publicado: (2022)

O011 Exploring Nocturnal Blood Pressure Surges Relationships with Brain Health and Cognitive Function.
por: Bull, C, et al.
Publicado: (2023)

O039 A Novel Approach to Quantify Breathing effort in Obstructive Sleep Apnoea
por: Nguyen, P, et al.
Publicado: (2023)

O038 Lower mean oxygen saturation in sleep is associated with worse cognitive performance in subjects with obstructive sleep apnoea
por: Atkins, L, et al.
Publicado: (2021)

O022 Long-term cardiovascular risk in obstructive sleep apnoea: a sleep clinic cohort study
por: Shenoy, B, et al.
Publicado: (2021)

P002 Targeted non-CPAP combination therapy resolves obstructive sleep apnoea
por: Aishah, A, et al.
Publicado: (2021)

O018 Improvement in Obstructive Sleep Apnoea Improves Heart Rate response to Obstructive Respiratory events in Children with Down syndrome.
por: Walter, L, et al.
Publicado: (2023)

Deformation, microstructure and stiffness of the rat brain tissue during the development of experimental obstructive hydrocephalus
por: Jugé, Lauriane, et al.
Publicado: (2015)

P002 Positive airway pressure adherence in children with sleep apnea may be similar to adults
por: Park, D, et al.
Publicado: (2023)

O042 Healthy lifestyle is Associated with Reduced Cardiovascular Disease, Depression and Mortality in People at Elevated risk of Sleep Apnea
por: Melaku, Y, et al.
Publicado: (2023)

O002: Patient and healthcare worker perception about patient participation in improving hand hygiene practices: impact of a patient participation intervention
por: Stewardson, AJ, et al.
Publicado: (2013)

P002 Antifungal activity of antimicrobial synthetic peptides against Candida species of public health importance
por: Torres, Richar, et al.
Publicado: (2022)

O012 Cardiovascular risk in a sleep clinic population with Obstructive Sleep Apnoea and association with symptom and polysomnographic profiles
por: Kemp, E, et al.
Publicado: (2022)

O011 Effect of Continuous Positive Airway Pressure on Quality of Life and Treatment Burden in Children with Obstructive Sleep Apnoea
por: Nisbet, L, et al.
Publicado: (2022)

O004 Obstructive sleep apnoea severity is associated with parasympathetic withdrawal in coronary artery disease
por: Ucak, S, et al.
Publicado: (2021)

O022 Characteristics of patients with obstructive sleep apnoea with a focus on the First Nations population
por: Bolger, M, et al.
Publicado: (2023)

O017 Real-World Utility of Overnight Oximetry for the Screening of Obstructive Sleep Apnoea in Children
por: Hartnett, C, et al.
Publicado: (2023)

O007 The impact of physical activity on sleepiness among patients with obstructive sleep apnoea. A study from the Sydney Sleep Biobank
por: Callum, J, et al.
Publicado: (2022)

O006 Major adverse cardiovascular events in severe Obstructive Sleep Apnoea: Associations with symptom subtypes and symptom burden
por: Shenoy, B, et al.
Publicado: (2023)

P002 CPAP therapy compliance and changes in cognitive function in patients with obstructive sleep apnoea
por: Adams, R, et al.
Publicado: (2022)

The use of ASET (Anti Staph Epidermidis Titre) in the diagnosis of ventriculo-atrial shunt infection
por: Reaper, Jacqueline, et al.
Publicado: (2010)

O056 Is Obstruction Obstructing Survival? Long-term Mortality in Patients with Chronic Obstructive Pulmonary Disease (COPD) requiring Acute Non-invasive Ventilation (NIV) with and without Obstructive sleep apnoea (OSA).
por: Nguyen, B, et al.
Publicado: (2023)

O019 Sleep spindles are reduced in children with Down syndrome and sleep disordered breathing
por: Shetty, M, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4p7e66lf6iotcuh1dhtuj4kisg