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Uncertainty analysis and optimization for mild moxibustion

During mild moxibustion treatment, uncertainties are involved in the operating parameters, such as the moxa-burning temperature, the moxa stick sizes, the stick-to-skin distance, and the skin moisture content. It results in fluctuations in skin surface temperature during mild moxibustion. Existing m...

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Autores principales: Liu, Honghua, Huang, Zhiliang, Wei, Lei, Huang, He, Li, Qian, Peng, Han, Liu, Mailan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109485/
https://www.ncbi.nlm.nih.gov/pubmed/37068075
http://dx.doi.org/10.1371/journal.pone.0282355
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author Liu, Honghua
Huang, Zhiliang
Wei, Lei
Huang, He
Li, Qian
Peng, Han
Liu, Mailan
author_facet Liu, Honghua
Huang, Zhiliang
Wei, Lei
Huang, He
Li, Qian
Peng, Han
Liu, Mailan
author_sort Liu, Honghua
collection PubMed
description During mild moxibustion treatment, uncertainties are involved in the operating parameters, such as the moxa-burning temperature, the moxa stick sizes, the stick-to-skin distance, and the skin moisture content. It results in fluctuations in skin surface temperature during mild moxibustion. Existing mild moxibustion treatments almost ignore the uncertainty of operating parameters. The uncertainties lead to excessive skin surface temperature causing intense pain, or over-low temperature reducing efficacy. Therefore, the interval model was employed to measure the uncertainty of the operation parameters in mild moxibustion, and the uncertainty optimization design was performed for the operation parameters. It aimed to provide the maximum thermal penetration of mild moxibustion to enhance efficacy while meeting the surface temperature requirements. The interval uncertainty optimization can fully consider the operating parameter uncertainties to ensure optimal thermal penetration and avoid patient discomfort caused by excessive skin surface temperature. To reduce the computational burden of the optimization solution, a high-precision surrogate model was established through a radial basis neural network (RBNN), and a nonlinear interval model for mild moxibustion treatment was formulated. By introducing the reliability-based possibility degree of interval (RPDI), the interval uncertainty optimization was transformed into a deterministic optimization problem, solved by the genetic algorithm. The results showed that this method could significantly improve the thermal penetration of mild moxibustion while meeting the skin surface temperature requirements, thereby enhancing efficacy.
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spelling pubmed-101094852023-04-18 Uncertainty analysis and optimization for mild moxibustion Liu, Honghua Huang, Zhiliang Wei, Lei Huang, He Li, Qian Peng, Han Liu, Mailan PLoS One Research Article During mild moxibustion treatment, uncertainties are involved in the operating parameters, such as the moxa-burning temperature, the moxa stick sizes, the stick-to-skin distance, and the skin moisture content. It results in fluctuations in skin surface temperature during mild moxibustion. Existing mild moxibustion treatments almost ignore the uncertainty of operating parameters. The uncertainties lead to excessive skin surface temperature causing intense pain, or over-low temperature reducing efficacy. Therefore, the interval model was employed to measure the uncertainty of the operation parameters in mild moxibustion, and the uncertainty optimization design was performed for the operation parameters. It aimed to provide the maximum thermal penetration of mild moxibustion to enhance efficacy while meeting the surface temperature requirements. The interval uncertainty optimization can fully consider the operating parameter uncertainties to ensure optimal thermal penetration and avoid patient discomfort caused by excessive skin surface temperature. To reduce the computational burden of the optimization solution, a high-precision surrogate model was established through a radial basis neural network (RBNN), and a nonlinear interval model for mild moxibustion treatment was formulated. By introducing the reliability-based possibility degree of interval (RPDI), the interval uncertainty optimization was transformed into a deterministic optimization problem, solved by the genetic algorithm. The results showed that this method could significantly improve the thermal penetration of mild moxibustion while meeting the skin surface temperature requirements, thereby enhancing efficacy. Public Library of Science 2023-04-17 /pmc/articles/PMC10109485/ /pubmed/37068075 http://dx.doi.org/10.1371/journal.pone.0282355 Text en © 2023 Liu et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Liu, Honghua
Huang, Zhiliang
Wei, Lei
Huang, He
Li, Qian
Peng, Han
Liu, Mailan
Uncertainty analysis and optimization for mild moxibustion
title Uncertainty analysis and optimization for mild moxibustion
title_full Uncertainty analysis and optimization for mild moxibustion
title_fullStr Uncertainty analysis and optimization for mild moxibustion
title_full_unstemmed Uncertainty analysis and optimization for mild moxibustion
title_short Uncertainty analysis and optimization for mild moxibustion
title_sort uncertainty analysis and optimization for mild moxibustion
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109485/
https://www.ncbi.nlm.nih.gov/pubmed/37068075
http://dx.doi.org/10.1371/journal.pone.0282355
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