Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range

Investigation of potential hosts of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is crucial to understanding future risks of spillover and spillback. SARS-CoV-2 has been reported to be transmitted from humans to various animals after requiring relatively few mutations. There is s...

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Detalles Bibliográficos
Autores principales: Ni, Dongchun, Turelli, Priscilla, Beckert, Bertrand, Nazarov, Sergey, Uchikawa, Emiko, Myasnikov, Alexander, Pojer, Florence, Trono, Didier, Stahlberg, Henning, Lau, Kelvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109501/
https://www.ncbi.nlm.nih.gov/pubmed/37018380
http://dx.doi.org/10.1371/journal.ppat.1011206

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