Farnesoid X receptor alpha ligands inhibit HDV in vitro replication and virion infectivity

HDV, a satellite of HBV, is responsible for the most severe form of human viral hepatitis, for which curative therapy is still awaited. Both HBV and HDV use the hepatic transporter of bile acids (ie, Na+-taurocholate cotransporting polypeptide) to enter hepatocytes. We have previously shown that lig...

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Detalles Bibliográficos
Autores principales: Legrand, Anne-Flore, Lucifora, Julie, Lacombe, Benoît, Ménard, Camille, Michelet, Maud, Foca, Adrien, Abrial, Pauline, Salvetti, Anna, Rivoire, Michel, Lotteau, Vincent, Durantel, David, André, Patrice, Ramière, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109841/
https://www.ncbi.nlm.nih.gov/pubmed/37058078
http://dx.doi.org/10.1097/HC9.0000000000000078

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