A Phase 2A Trial of the Safety and Tolerability of Increased Dose Rifampicin and Adjunctive Linezolid, With or Without Aspirin, for Human Immunodeficiency Virus–Associated Tuberculous Meningitis: The LASER-TBM Trial

BACKGROUND: Drug regimens that include intensified antibiotics alongside effective anti-inflammatory therapies may improve outcomes in tuberculous meningitis (TBM). Safety data on their use in combination and in the context of human immunodeficiency virus (HIV) are needed to inform clinical trial de...

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Detalles Bibliográficos
Autores principales: Davis, Angharad G, Wasserman, Sean, Stek, Cari, Maxebengula, Mpumi, Jason Liang, C, Stegmann, Stephani, Koekemoer, Sonya, Jackson, Amanda, Kadernani, Yakub, Bremer, Marise, Daroowala, Remy, Aziz, Saalikha, Goliath, Rene, Lai Sai, Louise, Sihoyiya, Thandi, Denti, Paolo, Lai, Rachel P J, Crede, Thomas, Naude, Jonathan, Szymanski, Patryk, Vallie, Yakoob, Banderker, Ismail Abbas, Moosa, Muhammed S, Raubenheimer, Peter, Candy, Sally, Offiah, Curtis, Wahl, Gerda, Vorster, Isak, Maartens, Gary, Black, John, Meintjes, Graeme, Wilkinson, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110270/
https://www.ncbi.nlm.nih.gov/pubmed/36482216
http://dx.doi.org/10.1093/cid/ciac932

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