Therapeutic targeting of vascular malformation in a zebrafish model of hereditary haemorrhagic telangiectasia

Hereditary haemorrhagic telangiectasia (HHT) causes arteriovenous malformations (AVMs) in multiple organs to cause bleeding, neurological and other complications. HHT is caused by mutations in the BMP co-receptor endoglin. We characterised a range of vascular phenotypes in embryonic and adult endogl...

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Detalles Bibliográficos
Autores principales: Snodgrass, Ryan O., Govindpani, Karan, Plant, Karen, Kugler, Elisabeth C., Doh, Changmin, Dawson, Thomas, McCormack, Luis E., Arthur, Helen M., Chico, Timothy J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110397/
https://www.ncbi.nlm.nih.gov/pubmed/36861761
http://dx.doi.org/10.1242/dmm.049567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110397/
https://www.ncbi.nlm.nih.gov/pubmed/36861761
http://dx.doi.org/10.1242/dmm.049567

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