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Therapeutic targeting of vascular malformation in a zebrafish model of hereditary haemorrhagic telangiectasia
Hereditary haemorrhagic telangiectasia (HHT) causes arteriovenous malformations (AVMs) in multiple organs to cause bleeding, neurological and other complications. HHT is caused by mutations in the BMP co-receptor endoglin. We characterised a range of vascular phenotypes in embryonic and adult endogl...
Autores principales: | Snodgrass, Ryan O., Govindpani, Karan, Plant, Karen, Kugler, Elisabeth C., Doh, Changmin, Dawson, Thomas, McCormack, Luis E., Arthur, Helen M., Chico, Timothy J. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110397/ https://www.ncbi.nlm.nih.gov/pubmed/36861761 http://dx.doi.org/10.1242/dmm.049567 |
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