HuR modulation counteracts lipopolysaccharide response in murine macrophages

Lipopolysaccharide (LPS) exposure to macrophages induces an inflammatory response, which is regulated at the transcriptional and post-transcriptional levels. HuR (ELAVL1) is an RNA-binding protein that regulates cytokines and chemokines transcripts containing AU/U-rich elements (AREs) and mediates t...

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Detalles Bibliográficos
Autores principales: Bonomo, Isabelle, Assoni, Giulia, La Pietra, Valeria, Canarutto, Giulia, Facen, Elisa, Donati, Greta, Zucal, Chiara, Genovese, Silvia, Micaelli, Mariachiara, Pérez-Ràfols, Anna, Robbiati, Sergio, Kontoyannis, Dimitris L., De Matteo, Marilenia, Fragai, Marco, Seneci, Pierfausto, Marinelli, Luciana, Arosio, Daniela, Piazza, Silvano, Provenzani, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110401/
https://www.ncbi.nlm.nih.gov/pubmed/36912171
http://dx.doi.org/10.1242/dmm.050120

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