Sp3 is essential for normal lung morphogenesis and cell cycle progression during mouse embryonic development

Members of the Sp family of transcription factors regulate gene expression via binding GC boxes within promoter regions. Unlike Sp1, which stimulates transcription, the closely related Sp3 can either repress or activate gene expression and is required for perinatal survival in mice. Here, we use RNA...

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Detalles Bibliográficos
Autores principales: McCoy, Alyssa M., Lakhdari, Omar, Shome, Sayane, Caoili, Kaitlin, Hernandez, Gilberto E., Aghaeepour, Nima, Butcher, Lindsay D., Fisch, Kathleen, Prince, Lawrence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110423/
https://www.ncbi.nlm.nih.gov/pubmed/36762637
http://dx.doi.org/10.1242/dev.200839

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