Cargando…

NANOGP1, a tandem duplicate of NANOG, exhibits partial functional conservation in human naïve pluripotent stem cells

Gene duplication events can drive evolution by providing genetic material for new gene functions, and they create opportunities for diverse developmental strategies to emerge between species. To study the contribution of duplicated genes to human early development, we examined the evolution and func...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maskalenka, Katsiaryna, Alagöz, Gökberk, Krueger, Felix, Wright, Joshua, Rostovskaya, Maria, Nakhuda, Asif, Bendall, Adam, Krueger, Christel, Walker, Simon, Scally, Aylwyn, Rugg-Gunn, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2023
Materias:	Stem Cells and Regeneration
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110494/ https://www.ncbi.nlm.nih.gov/pubmed/36621005 http://dx.doi.org/10.1242/dev.201155

Ejemplares similares

H3K9 tri-methylation at Nanog times differentiation commitment and enables the acquisition of primitive endoderm fate
por: Dubois, Agnès, et al.
Publicado: (2022)

NANOG/NANOGP8 Localizes at the Centrosome and is Spatiotemporally Associated with Centriole Maturation
por: Mikulenkova, Erika, et al.
Publicado: (2020)

Suppression of YAP safeguards human naïve pluripotency
por: Dattani, Anish, et al.
Publicado: (2022)

Epigenetic resetting of human pluripotency
por: Guo, Ge, et al.
Publicado: (2017)

The combined action of Esrrb and Nr5a2 is essential for murine naïve pluripotency
por: Festuccia, Nicola, et al.
Publicado: (2021)

In vivo functional studies of tumor-specific retrogene NanogP8 in transgenic animals
por: Badeaux, Mark A, et al.
Publicado: (2013)

TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells
por: Osnato, Anna, et al.
Publicado: (2021)

CRISPR/Cas9-mediated gene knockout of NANOG and NANOGP8 decreases the malignant potential of prostate cancer cells
por: Kawamura, Norihiko, et al.
Publicado: (2015)

Nanog1 in NTERA-2 and Recombinant NanogP8 from Somatic Cancer Cells Adopt Multiple Protein Conformations and Migrate at Multiple M.W Species
por: Liu, Bigang, et al.
Publicado: (2014)

Early forming label-retaining muscle stem cells require p27(kip1) for maintenance of the primitive state
por: Chakkalakal, Joe V., et al.
Publicado: (2014)

Regeneration of the aged thymus by a single transcription factor
por: Bredenkamp, Nicholas, et al.
Publicado: (2014)

Stochastic specification of primordial germ cells from mesoderm precursors in axolotl embryos
por: Chatfield, Jodie, et al.
Publicado: (2014)

A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification
por: Gilmour, Jane, et al.
Publicado: (2014)

Macrophages modulate adult zebrafish tail fin regeneration
por: Petrie, Timothy A., et al.
Publicado: (2014)

Coordinated repression and activation of two transcriptional programs stabilizes cell fate during myogenesis
por: Ciglar, Lucia, et al.
Publicado: (2014)

Exclusive multipotency and preferential asymmetric divisions in post-embryonic neural stem cells of the fish retina
por: Centanin, Lázaro, et al.
Publicado: (2014)

Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3
por: Osipovich, Anna B., et al.
Publicado: (2014)

Runx1 is required for progression of CD41(+) embryonic precursors into HSCs but not prior to this
por: Liakhovitskaia, Anna, et al.
Publicado: (2014)

Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes
por: Hoffmann, Stephanie A., et al.
Publicado: (2014)

Reconstruction of phrenic neuron identity in embryonic stem cell-derived motor neurons
por: Machado, Carolina Barcellos, et al.
Publicado: (2014)

Abdominal-B and caudal inhibit the formation of specific neuroblasts in the Drosophila tail region
por: Birkholz, Oliver, et al.
Publicado: (2013)

Growth/differentiation factor 15 promotes EGFR signalling, and regulates proliferation and migration in the hippocampus of neonatal and young adult mice
por: Carrillo-García, Carmen, et al.
Publicado: (2014)

The ERECTA receptor kinase regulates Arabidopsis shoot apical meristem size, phyllotaxy and floral meristem identity
por: Mandel, Tali, et al.
Publicado: (2014)

Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst
por: Le Bin, Gloryn Chia, et al.
Publicado: (2014)

Atypical protein kinase C couples cell sorting with primitive endoderm maturation in the mouse blastocyst
por: Saiz, Néstor, et al.
Publicado: (2013)

Recapitulation of morphogenetic cell shape changes enables wound re-epithelialisation
por: Razzell, William, et al.
Publicado: (2014)

Brg1 modulates enhancer activation in mesoderm lineage commitment
por: Alexander, Jeffrey M., et al.
Publicado: (2015)

Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification
por: O'Shaughnessy-Kirwan, Aoife, et al.
Publicado: (2015)

Selection and dynamics of embryonic stem cell integration into early mouse embryos
por: Alexandrova, Stoyana, et al.
Publicado: (2016)

Genes implicated in stem cell identity and temporal programme are directly targeted by Notch in neuroblast tumours
por: Zacharioudaki, Evanthia, et al.
Publicado: (2016)

Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification
por: Zdravkovic, Tamara, et al.
Publicado: (2015)

FGF/MAPK signaling sets the switching threshold of a bistable circuit controlling cell fate decisions in embryonic stem cells
por: Schröter, Christian, et al.
Publicado: (2015)

Regulation of Nematostella neural progenitors by SoxB, Notch and bHLH genes
por: Richards, Gemma Sian, et al.
Publicado: (2015)

The differential activation of intracellular signaling pathways confers the permissiveness of embryonic stem cell derivation from different mouse strains
por: Ohtsuka, Satoshi, et al.
Publicado: (2015)

mTOR regulates brain morphogenesis by mediating GSK3 signaling
por: Ka, Minhan, et al.
Publicado: (2014)

Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells
por: Turner, David A., et al.
Publicado: (2014)

Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells
por: van den Brink, Susanne C., et al.
Publicado: (2014)

Antagonism between Gdf6a and retinoic acid pathways controls timing of retinal neurogenesis and growth of the eye in zebrafish
por: Valdivia, Leonardo E., et al.
Publicado: (2016)

The ciliary marginal zone of the zebrafish retina: clonal and time-lapse analysis of a continuously growing tissue
por: Wan, Yinan, et al.
Publicado: (2016)

Concealed expansion of immature precursors underpins acute burst of adult HSC activity in foetal liver
por: Rybtsov, Stanislav, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_kpb3mutsn1to2s68ea7kb71mln