Quantifying label enrichment from two mass isotopomers increases proteome coverage for in vivo protein turnover using heavy water metabolic labeling

Heavy water metabolic labeling followed by liquid chromatography coupled with mass spectrometry is a powerful high throughput technique for measuring the turnover rates of individual proteins in vivo. The turnover rate is obtained from the exponential decay modeling of the depletion of the monoisoto...

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Detalles Bibliográficos
Autores principales: Deberneh, Henock M., Abdelrahman, Doaa R., Verma, Sunil K., Linares, Jennifer J., Murton, Andrew J., Russell, William K., Kuyumcu-Martinez, Muge N., Miller, Benjamin F., Sadygov, Rovshan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110577/
https://www.ncbi.nlm.nih.gov/pubmed/37069333
http://dx.doi.org/10.1038/s42004-023-00873-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110577/
https://www.ncbi.nlm.nih.gov/pubmed/37069333
http://dx.doi.org/10.1038/s42004-023-00873-x

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