Cargando…

CAR-T Therapies in Solid Tumors: Opportunities and Challenges

PURPOSE OF REVIEW: This review will discuss the challenges facing chimeric antigen receptor (CAR)-T cell application for solid tumors and opportunities to overcome these obstacles. In addition, this review will examine therapies that are in development for pediatric solid tumors. RECENT FINDINGS: Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guzman, Grace, Reed, Megan R., Bielamowicz, Kevin, Koss, Brian, Rodriguez, Analiz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110629/ https://www.ncbi.nlm.nih.gov/pubmed/36853475 http://dx.doi.org/10.1007/s11912-023-01380-x

Ejemplares similares

CAR T Cell Therapy for Pediatric Brain Tumors
por: Patterson, John D., et al.
Publicado: (2020)

CAR T cells in solid tumors: challenges and opportunities
por: Marofi, Faroogh, et al.
Publicado: (2021)

Combination of CAR‑T cell therapy and radiotherapy: Opportunities and challenges in solid tumors (Review)
por: Zhong, Liqiang, et al.
Publicado: (2023)

Chimeric-antigen receptor T (CAR-T) cell therapy for solid tumors: challenges and opportunities
por: Xia, An-Liang, et al.
Publicado: (2017)

Chimeric Antigen Receptors T Cell Therapy in Solid Tumor: Challenges and Clinical Applications
por: Mirzaei, Hamid R., et al.
Publicado: (2017)

Corrigendum: Chimeric Antigen Receptors T Cell Therapy in Solid Tumor: Challenges and Clinical Applications
por: Mirzaei, Hamid R., et al.
Publicado: (2019)

CAR T cell therapy and the tumor microenvironment: Current challenges and opportunities
por: Kankeu Fonkoua, Lionel A., et al.
Publicado: (2022)

CAR T Cells in Solid Tumors: Blueprints for Building Effective Therapies
por: Knochelmann, Hannah M., et al.
Publicado: (2018)

CAR-T Cell Therapy in Hematological Malignancies: Current Opportunities and Challenges
por: Zhang, Xiaomin, et al.
Publicado: (2022)

CAR T-Cell Therapy in Children with Solid Tumors
por: Kulczycka, Marika, et al.
Publicado: (2023)

Current advances and challenges in CAR T-Cell therapy for solid tumors: tumor-associated antigens and the tumor microenvironment
por: Yan, Ting, et al.
Publicado: (2023)

CAR-T cells and BiTEs in solid tumors: challenges and perspectives
por: Edeline, Julien, et al.
Publicado: (2021)

Efficacy, Safety, and Challenges of CAR T-Cells in the Treatment of Solid Tumors
por: Chen, Qiuqiang, et al.
Publicado: (2022)

CAR T-cell therapy in mature lymphoid malignancies: clinical opportunities and challenges
por: Narkhede, Mayur, et al.
Publicado: (2021)

Current Progress in CAR-T Cell Therapy for Solid Tumors
por: Ma, Shuo, et al.
Publicado: (2019)

Hurdles to breakthrough in CAR T cell therapy of solid tumors
por: Marofi, Faroogh, et al.
Publicado: (2022)

Clinical Investigations of CAR-T Cell Therapy for Solid Tumors
por: Chen, Kun, et al.
Publicado: (2022)

CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances
por: Maalej, Karama Makni, et al.
Publicado: (2023)

The current landscape of CAR T-cell therapy for solid tumors: Mechanisms, research progress, challenges, and counterstrategies
por: Daei Sorkhabi, Amin, et al.
Publicado: (2023)

CAR-T cells: Early successes in blood cancer and challenges in solid tumors
por: Dana, Hassan, et al.
Publicado: (2021)

Innovative CAR-T Cell Therapy for Solid Tumor; Current Duel between CAR-T Spear and Tumor Shield
por: Jo, Yuna, et al.
Publicado: (2020)

Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments
por: Dagar, Gunjan, et al.
Publicado: (2023)

317 Omics based analysis to identify novel markers of TMZ response in Glioblastoma Multiforme
por: Reed, Megan R., et al.
Publicado: (2023)

Combining chemotherapy with CAR-T cell therapy in treating solid tumors
por: Wang, Arthur Xuan, et al.
Publicado: (2023)

CAR T cell therapy in solid tumors: a short review
por: Umut, Öykü, et al.
Publicado: (2021)

Advances and Hurdles in CAR T Cell Immune Therapy for Solid Tumors
por: Boccalatte, Francesco, et al.
Publicado: (2022)

CAR T-Cell Immunotherapy Treating T-ALL: Challenges and Opportunities
por: Ren, Anqi, et al.
Publicado: (2023)

CAR-T Cells and Oncolytic Viruses: Joining Forces to Overcome the Solid Tumor Challenge
por: Guedan, Sonia, et al.
Publicado: (2018)

Rationally designed approaches to augment CAR-T therapy for solid tumor treatment
por: Zhu, Chaojie, et al.
Publicado: (2023)

Challenges and Opportunities Associated With Drug Delivery for the Treatment of Solid Tumors
por: Paresishvili, Teona, et al.
Publicado: (2023)

T-cell-engaging antibodies for the treatment of solid tumors: challenges and opportunities
por: Baeuerle, Patrick A., et al.
Publicado: (2022)

Correction: Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments
por: Dagar, Gunjan, et al.
Publicado: (2023)

Expanding the Therapeutic Window for CAR T Cell Therapy in Solid Tumors: The Knowns and Unknowns of CAR T Cell Biology
por: Watanabe, Keisuke, et al.
Publicado: (2018)

Bright future or blind alley? CAR-T cell therapy for solid tumors
por: Zhang, Kai, et al.
Publicado: (2023)

Mesothelin-targeted CAR-T cells for adoptive cell therapy of solid tumors
por: Zhang, Gui-Zhen, et al.
Publicado: (2019)

Emerging Approaches for Solid Tumor Treatment Using CAR-T Cell Therapy
por: Chung, Hyunmin, et al.
Publicado: (2021)

CAR T Cell Locomotion in Solid Tumor Microenvironment
por: Nguyen, Duy T., et al.
Publicado: (2022)

Enhancing T cell persistence of CAR-redirected T cells in solid tumors
por: Guedan, Sonia, et al.
Publicado: (2014)

Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors
por: Zhang, Hongru, et al.
Publicado: (2022)

Making CAR T Cells a Solid Option for Solid Tumors
por: Schmidts, Andrea, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4hvk1onf9g67rfugr67qeqa3nn