Generation of NK cells with chimeric-switch receptors to overcome PD1-mediated inhibition in cancer immunotherapy

Multiple myeloma (MM) is an incurable hematological cancer, in which immune checkpoint inhibition (ICI) with monoclonal antibodies (mAbs) has failed due to uncontrollable immune responses in combination therapies and lack of efficacy in monotherapies. Although NK cell-specific checkpoint targets suc...

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Detalles Bibliográficos
Autores principales: Susek, Katharina H., Schwietzer, Ysabel A., Karvouni, Maria, Gilljam, Mari, Keszei, Marton, Hussain, Alamdar, Lund, Johan, Kashif, Muhammad, Lundqvist, Andreas, Ljunggren, Hans-Gustaf, Nahi, Hareth, Wagner, Arnika K., Alici, Evren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110653/
https://www.ncbi.nlm.nih.gov/pubmed/36355079
http://dx.doi.org/10.1007/s00262-022-03317-y

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