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Brief report: STING expressed in tumor and non-tumor compartments has distinct roles in regulating anti-tumor immunity
Type I interferon-mediated activation of immune cells can facilitate the generation of productive tumor antigen-specific T cell responses in solid tumors. The cGAS/STING DNA sensing pathway is a critical upstream mediator of type I interferon production and is an important regulator of anti-tumor im...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110659/ https://www.ncbi.nlm.nih.gov/pubmed/36394642 http://dx.doi.org/10.1007/s00262-022-03327-w |