Brief report: STING expressed in tumor and non-tumor compartments has distinct roles in regulating anti-tumor immunity

Type I interferon-mediated activation of immune cells can facilitate the generation of productive tumor antigen-specific T cell responses in solid tumors. The cGAS/STING DNA sensing pathway is a critical upstream mediator of type I interferon production and is an important regulator of anti-tumor im...

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Detalles Bibliográficos
Autores principales: Kim, Jennie C., Liu, Xian, Fitzgerald, Karen, Eng, Jason S., Orf, Jessica, O’Brien, Sarah A., Belmontes, Brian, Casbon, Amy-Jo, Novitskiy, Sergey V., Tarbell, Kristin V., DeVoss, Jason, Egen, Jackson G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110659/
https://www.ncbi.nlm.nih.gov/pubmed/36394642
http://dx.doi.org/10.1007/s00262-022-03327-w

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