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The outcome of pregnancies after bariatric surgery: an observational study of pregnancies during 2004–2016 in Finland

PURPOSE: Overweight and obesity are major risk factors for perinatal morbidity and mortality, and the need for bariatric surgery (BS) among fertile-aged women is increasing. This study evaluates the outcome of post-BS pregnancies and deliveries. METHODS: All 20–45-year-old patients delivering betwee...

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Autores principales: Sesilia, Kaukonen, Susanna, Pajula, Virve, Koljonen, Mika, Gissler, Veli-Matti, Ulander, Marja, Kaijomaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110663/
https://www.ncbi.nlm.nih.gov/pubmed/36703011
http://dx.doi.org/10.1007/s00404-023-06935-8
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author Sesilia, Kaukonen
Susanna, Pajula
Virve, Koljonen
Mika, Gissler
Veli-Matti, Ulander
Marja, Kaijomaa
author_facet Sesilia, Kaukonen
Susanna, Pajula
Virve, Koljonen
Mika, Gissler
Veli-Matti, Ulander
Marja, Kaijomaa
author_sort Sesilia, Kaukonen
collection PubMed
description PURPOSE: Overweight and obesity are major risk factors for perinatal morbidity and mortality, and the need for bariatric surgery (BS) among fertile-aged women is increasing. This study evaluates the outcome of post-BS pregnancies and deliveries. METHODS: All 20–45-year-old patients delivering between 2004 and 2016 in Finland were included. Patients with previous BS were identified from the hospital discharge register, and the medical birth register was queried for data on pregnancies, deliveries, and perinatal outcomes. The data were matched using personal identification codes, and the outcomes of women with previous BS were compared with those of other pregnancies. RESULTS: Women with previous BS (n = 314) constituted the bariatric group. When compared with the non-bariatric group (n = 750,019), they were older (p < 0.001), heavier (p < 0.001) and had more previous pregnancies (p < 0.001). The overall incidence of pregnancy-induced hypertension (p = 0.002), gestational diabetes (GDM) (p = 0.018), pre-term contractions (p = 0.023), pre-term delivery (p = 0.003), labour induction (p < 0.001), planned (p = 0.001) and unplanned (p = 0.036) caesarean sections and low birthweight infants (p < 0.001) were significantly higher in the bariatric group. When compared with body mass index–specific categories, the main outcomes were increased incidence of GDM and small for gestational age (SGA) newborns in the bariatric group. CONCLUSION: BS can be considered a safe and advisable treatment for obesity among fertile-aged women. The pregnancy outcome is associated with post-BS weight, but the risk for GDM and small for gestational-age newborns is increased.
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spelling pubmed-101106632023-04-19 The outcome of pregnancies after bariatric surgery: an observational study of pregnancies during 2004–2016 in Finland Sesilia, Kaukonen Susanna, Pajula Virve, Koljonen Mika, Gissler Veli-Matti, Ulander Marja, Kaijomaa Arch Gynecol Obstet Gynecologic Endocrinology and Reproductive Medicine PURPOSE: Overweight and obesity are major risk factors for perinatal morbidity and mortality, and the need for bariatric surgery (BS) among fertile-aged women is increasing. This study evaluates the outcome of post-BS pregnancies and deliveries. METHODS: All 20–45-year-old patients delivering between 2004 and 2016 in Finland were included. Patients with previous BS were identified from the hospital discharge register, and the medical birth register was queried for data on pregnancies, deliveries, and perinatal outcomes. The data were matched using personal identification codes, and the outcomes of women with previous BS were compared with those of other pregnancies. RESULTS: Women with previous BS (n = 314) constituted the bariatric group. When compared with the non-bariatric group (n = 750,019), they were older (p < 0.001), heavier (p < 0.001) and had more previous pregnancies (p < 0.001). The overall incidence of pregnancy-induced hypertension (p = 0.002), gestational diabetes (GDM) (p = 0.018), pre-term contractions (p = 0.023), pre-term delivery (p = 0.003), labour induction (p < 0.001), planned (p = 0.001) and unplanned (p = 0.036) caesarean sections and low birthweight infants (p < 0.001) were significantly higher in the bariatric group. When compared with body mass index–specific categories, the main outcomes were increased incidence of GDM and small for gestational age (SGA) newborns in the bariatric group. CONCLUSION: BS can be considered a safe and advisable treatment for obesity among fertile-aged women. The pregnancy outcome is associated with post-BS weight, but the risk for GDM and small for gestational-age newborns is increased. Springer Berlin Heidelberg 2023-01-26 2023 /pmc/articles/PMC10110663/ /pubmed/36703011 http://dx.doi.org/10.1007/s00404-023-06935-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Gynecologic Endocrinology and Reproductive Medicine
Sesilia, Kaukonen
Susanna, Pajula
Virve, Koljonen
Mika, Gissler
Veli-Matti, Ulander
Marja, Kaijomaa
The outcome of pregnancies after bariatric surgery: an observational study of pregnancies during 2004–2016 in Finland
title The outcome of pregnancies after bariatric surgery: an observational study of pregnancies during 2004–2016 in Finland
title_full The outcome of pregnancies after bariatric surgery: an observational study of pregnancies during 2004–2016 in Finland
title_fullStr The outcome of pregnancies after bariatric surgery: an observational study of pregnancies during 2004–2016 in Finland
title_full_unstemmed The outcome of pregnancies after bariatric surgery: an observational study of pregnancies during 2004–2016 in Finland
title_short The outcome of pregnancies after bariatric surgery: an observational study of pregnancies during 2004–2016 in Finland
title_sort outcome of pregnancies after bariatric surgery: an observational study of pregnancies during 2004–2016 in finland
topic Gynecologic Endocrinology and Reproductive Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110663/
https://www.ncbi.nlm.nih.gov/pubmed/36703011
http://dx.doi.org/10.1007/s00404-023-06935-8
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