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Generation of a symmetrical trispecific NK cell engager based on a two-in-one antibody
To construct a trispecific IgG-like antibody at least three different binding moieties need to be combined, which results in a complex architecture and challenging production of these molecules. Here we report for the first time the construction of trispecific natural killer cell engagers based on a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110854/ https://www.ncbi.nlm.nih.gov/pubmed/37081888 http://dx.doi.org/10.3389/fimmu.2023.1170042 |