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Metabolomics-based discovery of XHP as a CYP3A4 inhibitor against pancreatic cancer

Background: Xihuang Wan (XHW), a purgative and detoxifying agent, is commonly utilized in modern medicine as a treatment and adjuvant therapy for various malignancies, including breast cancer, liver cancer, and lung cancer. A clinical study demonstrated the potential usefulness of the combination of...

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Detalles Bibliográficos
Autores principales:	Yang, Yuting, Guo, Yanlei, Luo, Hua, Wang, Menglei, Chen, Fang, Cui, Huawei, Chen, Ping, Yin, Zhujun, Li, Li, Dai, Ying, Zeng, Jin, Zhao, Junning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110895/ https://www.ncbi.nlm.nih.gov/pubmed/37081969 http://dx.doi.org/10.3389/fphar.2023.1164827

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