Pediatric heart transplant rejection following COVID-19 infection

BACKGROUND: Infections have been associated with rejection episodes in solid organ transplant recipients. We report an association between COVID-19 infection and heart transplant (HT) rejection. CASE DESCRIPTION: The patient was 14 years old and 6.5 years post-HT. He developed symptoms of rejection...

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Detalles Bibliográficos
Autores principales: Shea, Erin V., Sinicropi, Natalie L., Cusick, Matthew F., Rabah, Raja, Lim, Heang M., Schumacher, Kurt R., McCormick, Amanda D., Peng, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110939/
https://www.ncbi.nlm.nih.gov/pubmed/37188611
http://dx.doi.org/10.1016/j.transproceed.2023.04.021
Descripción
Sumario:BACKGROUND: Infections have been associated with rejection episodes in solid organ transplant recipients. We report an association between COVID-19 infection and heart transplant (HT) rejection. CASE DESCRIPTION: The patient was 14 years old and 6.5 years post-HT. He developed symptoms of rejection within two weeks of COVID exposure and presumed infection. CONCLUSIONS: In this case, COVID-19 infection closely preceded significant rejection and graft dysfunction. Further study is needed to establish a correlation between COVID-19 infection and rejection in heart transplant patients.

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